University of Leicester - Pathology Other titles Times New Roman Arial Georgia Symbol lwblugrad35 PowerPoint Presentation Introduction Introduction Types of insult - hypoxia Types of insult - chemical Types of insult - infections Types of insult - Physical Types of insult immune Types of. immune reactions. Injured cell. Cell Injury I Cell Injury and Cell Death Dept. Cell death-necrosis 3. Now, it is more appropriately called chronic traumatic brain injury (CTBI), by neuroscientists, neurologists, and neurosurgeons. 2 billion in 2021 at a compound annual growth rate (CAGR) of 18. Cellular injury initiation. Coagulative NecrosisIt is most common type. com - id 4c05f3-MjI3Y. Asbestos-Associated Diseases. . For example, the histologic changes of injury after 3 h of feline intestinal ischemia followed by 1 h of reperfusion are far worse than the changes observed after 4 h of ischemia alone. Hypoxia (loss of aerobic oxidative respiration) vs. 4 Inflammation I Compatibility Mode Author rmo5 Created Date 2142011 81918 PM. pptx from HEMATOLOGY 202 at DOW University of Health Sciences, Karachi. As DM, halving the falling damage is what I typically do. Pathology is a scientific study of the nature of discuse and its causes, processes, mechanism and effects are also called pathology. Cell injury is a sequence of events that occur if the limits of adaptive capability are exceeded or no adaptive response is possible. The get the sign, hold the zero number until it changes to a plus sign. fCell Injury Hypertrophy. Lecture Title Cell injury. chamicals and drugs. Maintained by homeostasis. Various forms of cellular responses to cell injury (cellular adaptations) (reversible cell injury) (irreversible cell injury). , burns or frostbite; irradiation; chemicals) 4. Irreversible cell injury 3. ischemia) Coagulative necrosis Occurs in hypoxic tissue Structural proteins bend out of shape Lysosomal proteins become ineffective. Cell injury results from biochemical and functional abnormalities in the. There are 5 types of Necrosis1)Coagulative necrosis 2)liquification (colliquative) necrosis. PATHOLOGY CELL INJURY ADAPTATION and DEATH. CELL INJURY Dr Gerald Saldanha Dept of Pathology Introduction This presentation will be a guide to cell injury and cell death outline causes and pathogenesis of cell injurydeath describe the morphological changes of cell injurydeath Describe the process of apoptosis Introduction General considerations Adapt or die. Robert Low MD PhD. As DM, halving the falling damage is what I typically do. Getting hit in the head repeatedly causes chronic neurological problems, which used to be called "Punch-Drunk Syndrome". STATUS DARAH DAN TITER NEWCASTLE DISEASE PADA BURUNG PUYUH PETELUR YANG DIBERI RANSUM MENGGUNAKAN TEPUNG DAUN OROK-OROK. txt) or view presentation slides online. Physical and chemical agents (thermal injury, e. The affected cells may recover from the injury called Reversible injury; if cell may die, it is called Irreversible it. - Literally Pathology is the study (logos) of disease (pathos, suffering). A basic cell is bounded by a cell membrane. Jul 5, 2021 Cellular Adaptation to Injury or Stress Injury or Stress Increased demand Decreased stimulation or lack of nutrients Chronic irritation Adaptation Hyperplasia or hypertrophy Atrophy Metaplasia Slide 3- ppt slide no 3 content not found Slide 4- Adapted - Normal - Injured Cells Slide 5- Adaptations Hypertrophy Hyperplasia Atrophy Metaplasia. Cell injury pathology ppt. CELL INJURY, ADAPTATION, and DEATH Normal cell is in a . Pathogenesis and morphology of cell injury. Cell injury pathology ppt. Reversible cell injury 2. This chapter will discuss cellular adaptation, cell injury, cellular accumulations, and cellular aging. Infections (bacterial, viral, parasitic) 2. Roughly covered in Immune Pathology Infectious Cell Injury Microbial insult can occur via direct release of cellular toxins or intracellular infection Genetic Cell Injury These refer to insults due to hereditary defects in key cellular proteins. Introduction Pathology . ABDULATTAH Lecturer in pathology departmentMousel Medical college Cell Injury, Cell Death, and Adaptations Lecture 2 Types (Patterns) of necrosis coagulation necrosis liquifactive necrosisfat necrosiscaseous necrosisfibrinoid necrosis gangrene. Cell Injury. Robert Low MD PhD. Apoptosis 4. The white blood cells must then leave the blood vessel, cross the basement membrane, and be drawn to the area where they are needed. Al-Nueimy Professor Department of Pathology University of Mosul 21st October 2015 Factors that determine fate of cells1-Type of injury (chemical or physical. of Pathology. Injury may progress through a reversible stage. Molecular mechanisms (1) ATP loss causes failure of biosynthesis and ion. pdf), Text File (. Everything you need to know about cell injury, causes, mechanism, different types of cell injury. with mild injury to cells that have the capacity to enter the cell cycle - e. the mode of action of specific organic and inorganic chemicals. Various forms of cellular responses to cell injury (cellular adaptations) (reversible cell injury) (irreversible cell injury). PowerPoint PPT presentation free to view. Key Concepts <ul><li>Normal cells have a fairly narrow range . Pathology includes study of etiology (what initiates a process), pathogenesis (mechanism), . Human Pathology Dr. Cell injury. 4 Inflammation I Compatibility Mode Author rmo5 Created Date 2142011 81918 PM. Cell injury and cell responses Dr. Excess physiologic or pathologic stress may force the cell to a new steady stateAdaptation. pumps cloudy swelling. Expository Preaching lesson 4 1. 1 (min > dakota scott) 1. The affected cells may recover from the injury called Reversible injury; if cell may die, it is called Irreversible it. View Lecture 1- Cell Injury. 4 Inflammation I Compatibility Mode Author rmo5 Created Date 2142011 81918 PM. There are many more causes like chemical injury, cellular aging, hyperoxia, killing of exogenious biological agents, destruction of tumor cells, inflammatory damage, chemical injuries, ionization, artherosclerogenesis. It is an intracytoplasmic accumulation of water due to incapacity of the cells to maintain the ionic and fluid homeostasis. 3-Duration of exposure (short or long). Enlist types of necrosis. Roughly covered in Immune Pathology Infectious Cell Injury Microbial insult can occur via direct release of cellular toxins or intracellular infection Genetic Cell Injury These refer to insults due to hereditary defects in key cellular proteins. 2-Severity of injury(Mild or moderate or sever). Title Cell Injury and Adaptation 1 1 Cell Injury and Adaptation 1. Causes of Acute inflammation 1. infection or injury; Causes rupturing of cells and leakage of their . Intracellular accumulations 6. Temur Ahsan Khan. Functional change. Deranged cell metabolism 6. Apr 18, 2017 Classification of morphologic forms of cell injury 1. Bronchodilation Vasodilation General Response to Injury Cellular. Cellular reaction How Chemical mediators. Bronchodilation Vasodilation General Response to Injury Cellular. CLINICAL TRIALS. 4-Type of cells. of Pathology. The crash happened around 630 p Explore Wichita Falls 's sunrise and sunset, moonrise and moonset , Saturday, Oct Miami Daily News-Record Oklahoma 1955-03-18 The Transportation Ministry has attributed a notable decrease in the number of traffic accidents during the exodus season to travelers shifting to toll National data collected by the National Police Traffic Corps. Cell injury pathology ppt. Cell and tissue injury produce human disease Injury-acute vs chronic sites within cells that are easily injured reversibility of injury and complete recover adaptation to chronic injury cell death-necrosis vs apoptosis Hypoxic injury-starving cellstissues for oxygen; problems of too much oxygen and cell damage from oxygen radicals. Cells and Tissue -- A Nice Power Point Presentaion. Pathophysiology involves the study of functional or physiologic changes in the body that result from disease processes. Functional change. pdf), Text File (. Balancing control mechanism aimed at maintaining constant condition. Now, it is more appropriately called chronic traumatic brain injury (CTBI), by neuroscientists, neurologists, and neurosurgeons. Cellular adaptations to cell injury and cell death Banun Kusumawardani 1 Definitions - Pathology - The study of disease - Clinical Pathology . 4 Inflammation I Compatibility Mode Author rmo5 Created Date 2142011 81918 PM. Nursing Students Extension ProgramCellular swelling occurs with impairment of the energy-dependent NaK-ATPase membrane pump, usually as the result of hypoxic cell injury. What causes Groin strains Groin strain occurs when the adductor muscles are overstretched, and is usually a result of a side stepping action, twisting motion or a sudden change of direction. Cell Injury - 4 interrelated cell systems especially susceptible to injury o Membranes (cellular and organellar) o Aerobic system o Protein synthesis (enzymes, structural proteins, etc) o Genetic apparatus (DNA, RNA, etc) - Mechanisms for cell injury o Loss of Ca homeostasis o Membrane permeability defects o ATP depletion o O 2 and O 2. View 2. This chapter will discuss cellular adaptation, cell injury, cellular accumulations, and cellular aging. 3-Duration of exposure (short or long). Clinical Practice Guidelines. Pathology cell injury i. ppt Dr. Cell Injury I Cell Injury and Cell Death Dept. Cell Injury 17 Lecture4 - Free download as Powerpoint Presentation (. The get the sign, hold the zero number until it changes to a plus sign. 2 billion in 2021 at a compound. Semester 2 Benign and Malignant Tumours. This chapter will discuss cellular adaptation, cell injury, cellular accumulations, and cellular aging. Introduction to pathology. Nursing Students Extension ProgramCellular swelling occurs with impairment of the energy-dependent NaK-ATPase membrane pump, usually as the result of hypoxic cell injury. Cell Injury 1 Cell Injury 2. Cell Injury General Mechanisms Four very interrelated cell systems are particularly vulnerable to injury Membranes (cellular and organellar) Aerobic respiration Protein synthesis (enzymes, structural proteins, etc) Genetic apparatus (e. Cell Injury, Death, Inflammation, and Repair J. View 2. Factors pertaining to injurious agent extent & type of cell injury. protein kinases phosphorylation of protein. When there is partial or total deprivation of oxygen for tissues. Pathogenesis and morphology of cell injury. Programmed cell death 4. Ischemia injures cells more than hypoxia. email protected Cellular Adaptations Given stressors, cells respond by changing their size. cell injury results when the cell can no longer adapt to the stress, which can be reversible implies that once the stress is removed the cell can return to its original state irreversible when the stressful stimuli is excessive or persistent the cellular damage becomes irreversible and cells undergo cell death General mechanism of cell injury. ca HLSC. The affected cells may recover from the injury called Reversible injury; if cell may die, it is called Irreversible it. Ischemic heart disease Pathology 4 aspects of disease 1. As DM, halving the falling damage is what I typically do. rar Dr. If the cells fail to adapt under stress, they undcrgo certain changes leading to Cell injury. of Pathology. 100 (1) Pages 5 20222023. Log In My Account wu. Key Concepts. com -. Cell Injury 17 Lecture4 - Free download as Powerpoint Presentation (. Studying NSG 120 Nursing Pathophysiology at Herzing University On StuDocu you will find 43 Mandatory assignments, Practice Materials, Lecture notes , Practical and. infection, temperature) Internal triggers (e. ca HLSC. 0 Slides 32 Provided by janusNort Category. Causes and mechanisms of cell injury. Rebecca MacPherson Office STH 310 Hours Mondays 9-10am email email protected HLSC. Cell death occurs when the severity of the . functional demand or. activates intracellular enzymes and causes cell. There are many more causes like chemical injury, cellular aging, hyperoxia, killing of exogenious biological agents, destruction of tumor cells, inflammatory damage, chemical injuries, ionization, artherosclerogenesis. Hypertrophy is an increase in cell size by gain of. If the cells fail to adapt under stress, they undcrgo certain changes leading to Cell injury. Programmed cell death 4. Effects on cells, tissues, and organs 3 Cell Injury, Adaptation, and Cell Death Normal cellular function Physiologic parameters. Jul 5, 2021 Cellular Adaptation to Injury or Stress Injury or Stress Increased demand Decreased stimulation or lack of nutrients Chronic irritation Adaptation Hyperplasia or hypertrophy Atrophy Metaplasia Slide 3- ppt slide no 3 content not found Slide 4- Adapted - Normal - Injured Cells Slide 5- Adaptations Hypertrophy Hyperplasia Atrophy Metaplasia. Pathology is a scientific study of the nature of discuse and its causes, processes, mechanism and effects are also called pathology. Cell Injury - 4 interrelated cell systems especially susceptible to injury o Membranes (cellular and organellar) o Aerobic system o Protein synthesis (enzymes, structural proteins, etc) o Genetic apparatus (DNA, RNA, etc) - Mechanisms for cell injury o Loss of Ca homeostasis o Membrane permeability defects o ATP depletion o O 2 and O 2. PATHOLOGY Lecture 1 Cell injury and cell death Causes of Description PATHOLOGY Lecture 1 Cell injury and cell death Causes of cell injury hypoxia oxygen deprivation physical agents (temperature extremes, pressure, electric shock. Various forms of cellular responses to cell injury (cellular adaptations) (reversible cell injury) (irreversible cell injury) 3. functional demand or. Corpora amylacea. Pulmonary pathology for medical students. protein kinases phosphorylation of protein. activates intracellular enzymes and causes cell. ByDr Abiodun Mark Akanmode. Cellular Pathology 1. After-effects NOMENCLATURE 1. Introduction Pathology . Ron Luff, MD, MPH. Reversible cell injury 2. If the cells fail to adapt under stress, they undcrgo certain changes leading to Cell injury. Programmed cell death 4. chamicals and drugs. Aerobic respiration involving mitochondrial oxidative phosphorylation and production of ATP. Cell Injury and Adaptation 1 Basic Cell Pathology Robbins (7th edition), Chapter 1 2 Cell Injury and Adaptation Basic and clinical science Injurious agent Structural change. 4 Inflammation I Compatibility Mode Author rmo5 Created Date 2142011 81918 PM. There are 5 types of Necrosis1)Coagulative necrosis 2)liquification (colliquative) necrosis. of Pathology. Physical and chemical agents (thermal injury, e. cell injury results when the cell can no longer adapt to the stress, which can be reversible implies that once the stress is removed the cell can return to its original state irreversible when the stressful stimuli is excessive or persistent the cellular damage becomes irreversible and cells undergo cell death General mechanism of cell injury. Reversible cell injury can result in changes which may recover when the cause is removed, or which may persist. Microsoft PowerPoint - 2. of Pathology. Mar 15, 2013 Salmonella spp, other Clostridium spp, and Brucella spp can cause this type of lesion in many species. Definition An expository sermon is a sermon whose structure is determined by a Scriptural unit of thought, whose substance is determined by the thorough exegesis of the text and the congregation, and whose success is dependent on the Spirit of God empowering the servant of God to explain, illustrate, and apply the truth of God in such a way. Cell Injury Cell injury is defined as a variety of stresses a cell encounters as a result of changes in its internal and external environment. Some of these skeletal muscle fibers here show atrophy, compared to normal fibers. Hypoxia (loss of aerobic oxidative respiration) vs. rp Pathology is a scientific study of the nature of discuse and its causes, processes, mechanism and effects are also called pathology. ABDULATTAH Lecturer in pathology departmentMousel Medical college Cell Injury, Cell Death, and Adaptations Lecture 2 Types (Patterns) of necrosis coagulation necrosis liquifactive necrosisfat necrosiscaseous necrosisfibrinoid necrosis gangrene. A basic cell is bounded by a cell membrane. . CELL INJURY Dr Gerald Saldanha Dept of Pathology. Rebecca MacPherson Office STH 310 Hours Mondays 9-10am email email protected HLSC. Rebecca MacPherson Office STH 310 Hours Mondays 9-10am email rmacphersonbrocku. Mallorys hyaline 4. Pathology is a scientific study of the nature of discuse and its causes, processes, mechanism and effects are also called pathology. with mild injury to cells that have the capacity to enter the cell cycle - e. ppt from HLSC 4P95 at Brock University. Genetic derangements 7. 100 (1) Pages 5 20222023. Pathology is a scientific study of the nature of discuse and its causes, processes, mechanism and effects are also called pathology. of Pathology. KHALID W. With the involvement of a sufficient number of. injured cell. cw Best overall; mq Best for beginners building a professional blog; zc Best for artists, and designers; jd Best for networking; bw Best for writing to a built-in audience. This chapter will discuss cellular adaptation, cell injury, cellular accumulations, and cellular aging. Cell Death. A long tradition defines the scope of pathology as both a clinical specialty and an area of biomedical research. How to donate 1. dillon latham leaked nudes, ibc routing number san antonio
It is an intracytoplasmic accumulation of water due to incapacity of the cells to maintain the ionic and fluid homeostasis. . Cell injury pathology ppt
The number of myocardial fibers does not increase, but their size can increase in response to an increased workload, leading to the marked thickening of the left ventricle in this patient with systemic hypertension. Effects on cells, tissues, and organs 3 Cell Injury, Adaptation, and Cell Death Normal cellular function Physiologic parameters. NECROSISIt is focal death of cell along with degeneration of tissue by hydrolytic enzyme liberated by cells. Cellular adaptation cell injury and cell death. I am not sure how to send a text to Italy, but you could try sending it just like a normal text if it is a U. A long tradition defines the scope of pathology as both a clinical specialty and an area of biomedical research. Rebecca MacPherson Office STH 310 Hours Mondays 9-10am email email protected HLSC. cells, an entire organ can become hypertrophic. Cell Injury General Mechanisms Four very interrelated cell systems are particularly vulnerable to injury Membranes (cellular and organellar) Aerobic respiration Protein synthesis (enzymes, structural proteins, etc) Genetic apparatus (e. pumps cloudy swelling. Physical agents (temperature, trauma, radiation) 3. Apoptosis may be a mechanism to eliminate worn-out or genetically damaged cells. - Literally Pathology is the study (logos) of disease (pathos, suffering). Although rooted in the correlation of anatomical and histological changes with clinically apparent disease (and hence the iconic images of autopsy and microscope), modern pathology studies the causes of disease (etiology) and the expressionevolution of such (pathogenesis) at the. Cells and Tissue -- A Nice Power Point Presentaion. first degree burn. PowerPoint PPT presentation Number of Views 4424 Avg rating3. A long tradition defines the scope of pathology as both a clinical specialty and an area of biomedical research. Overview The four basic types of cellular adaptation to be discussed in this section are hyperplasia, hypertrophy, atrophy, and metaplasia. Damage to plasma membrane sodium pump. Physical agents (temperature, trauma, radiation) 3. There are many more causes like chemical injury, cellular aging, hyperoxia, killing of exogenious biological agents, destruction of tumor cells, inflammatory damage, chemical injuries, ionization, artherosclerogenesis. Effects on cells, tissues, and organs 3 Cell Injury, Adaptation, and Cell Death Normal cellular function Physiologic parameters. Duke University Medical School - Histology. - Recognize the different types of necrosis. occurring in the living body. These changes can lead to cell injury, fibrosis, and possibly cancer; Asbestos is genotoxic and carcinogenic. Al-Nueimy Professor Department of Pathology University of Mosul 21st October 2015 Factors that determine fate of cells1-Type of injury (chemical or physical. Using this method, even a thousand-foot fall into the ocean would only inflict 10d6 bludgeoning damage. A long tradition defines the scope of pathology as both a clinical specialty and an area of biomedical research. Cell Injury. Pathology Dr. 4 Inflammation I Compatibility Mode Author rmo5 Created Date 2142011 81918 PM. Damage to membranes is severe, lysosomal enzymes enter the cytoplasm and digest the cell, and cellular contents leak. Foreign bodies (splinter, dirt, sutures) 6. A long tradition defines the scope of pathology as both a clinical specialty and an area of biomedical research. -Identify the differences between apoptosis and necrosis. even wrecked diesel pickups. ppt Dr. 12 Diagnosis of infections with these etiologic agents can be made on the basis of results of bacterial culture of or viral isolation from affected tissue samples and compatible clinical signs or necropsy findings. fCell Injury Hypertrophy. Excess physiologic or pathologic stress may force the cell to a new steady stateAdaptation. com - id 4c05f3-MjI3Y. Al-Nueimy Professor Department of Pathology University of Mosul 21st October 2015 Factors that determine fate of cells1-Type of injury (chemical or physical. A long tradition defines the scope of pathology as both a clinical specialty and an area of biomedical research. Cellular reaction How Chemical mediators. , DNA, RNA) 6. PATHOGENESIS Of reversible cell injury If ischemia of short time effects are reversible Sequential changes in reversible cell injury Decrease cellular ATP. Ch GN 5. Cellular Adaptation to Injury or Stress Injury or Stress Increased demand Decreased stimulation or lack of nutrients Chronic irritation Adaptation Hyperplasia or hypertrophy Atrophy Metaplasia Slide 3- ppt slide no 3 content not found Slide 4- Adapted - Normal - Injured Cells Slide 5- Adaptations Hypertrophy Hyperplasia Atrophy Metaplasia. Al-Nueimy Professor Department of Pathology University of Mosul 21st October 2015 Factors that determine fate of cells1-Type of injury (chemical or physical. 2 billion in 2021 at a compound. immune reactions. It indicates, "Click to perform a search". 4-Type of cells. Definition Cell injury The effect of a variety of stresses due to etiological agents a cell encounters resulting in changes in its internal & external environment. Apoptosis may be a mechanism to eliminate worn-out or genetically damaged cells. Study related questions. Pathogenesis and morphology of cell injury. rar Dr. The affected cells may recover from the injury called Reversible injury; if cell may die, it is called Irreversible it. University of Leicester - Pathology Other titles Times New Roman Arial Georgia Symbol lwblugrad35 PowerPoint Presentation Introduction Introduction Types of insult - hypoxia Types of insult - chemical Types of insult - infections Types of insult - Physical Types of insult immune Types of. These changes can lead to cell injury, fibrosis, and possibly cancer; Asbestos is genotoxic and carcinogenic. Digital Pathology in the Era of Global Clinical Trials Improving Quality and Consistency. Question Why is bigger not always better. in cell injury (Reference Robbins and Cotrans Pathologic Basis of Diseases. There are 5 types of Necrosis1)Coagulative necrosis 2)liquification (colliquative) necrosis. Foreign bodies (splinter, dirt, sutures) 6. A long tradition defines the scope of pathology as both a clinical specialty and an area of biomedical research. Cell Injury This is cardiac hypertrophy involving the left ventricle. 4-Type of cells. Rebecca MacPherson Office STH 310 Hours Mondays 9-10am email rmacphersonbrocku. Cells and Tissue -- A Nice Power Point Presentaion. How to Prevent Fall Damage 5e. Cell Injury and Cell Death Imhotep Virtual Medical School. shoaib raza associate professor, pathology, rihs adaptation of cellular growth and differentiation cell injury-1 objective the objectives of this lecture are introduce the term adaptation and cell injury define and brief explanation of various forms of adaptation; like hypertrophy hyperplasia atrophy metaplasia cell injury. Cell Injury I Cell Injury and Cell Death Dept. Pulmonary pathology for medical students. Rebecca MacPherson Office STH 310 Hours Mondays 9-10am email rmacphersonbrocku. how to . Search Forensic Ballistics Notes Pdf. Click on "PROCEED TO CHECKOUT". Gross Kidney,swelling. Cell death occurs when the severity of the . There are many more causes like chemical injury, cellular aging, hyperoxia, killing of exogenious biological agents, destruction of tumor cells, inflammatory damage, chemical injuries, ionization, artherosclerogenesis. ABDULATTAH Lecturer in pathology departmentMousel Medical college Cell Injury, Cell Death, and Adaptations Lecture 2 Types (Patterns) of necrosis coagulation necrosis liquifactive necrosisfat necrosiscaseous necrosisfibrinoid necrosis gangrene. Intro is now included as part of Fundamentals of Nursing , and F&E and Acid Base are now included as part of Medical Surgical Nursing I. Microsoft PowerPoint - 2. If the cells fail to adapt under stress, they undcrgo certain changes leading to Cell injury. Jul 5, 2021 Cellular Adaptation to Injury or Stress Injury or Stress Increased demand Decreased stimulation or lack of nutrients Chronic irritation Adaptation Hyperplasia or hypertrophy Atrophy Metaplasia Slide 3- ppt slide no 3 content not found Slide 4- Adapted - Normal - Injured Cells Slide 5- Adaptations Hypertrophy Hyperplasia Atrophy Metaplasia. Human Pathology Dr. This is a response to injury by "downsizing" to conserve the cell. Title MITOCHONDRIA BIOLOGY Author Default Created Date 9232002 21152 AM Document presentation format On-screen Show (43) Company chlamybioposse Other titles. Cell Injury I Cell Injury and Cell Death Dept. Al-Nueimy Professor Department of Pathology University of Mosul 21st October 2015 Factors that determine fate of cells1-Type of injury (chemical or physical. edu Cellular Adaptations Given stressors, cells respond by changing their size. Functional change. Although rooted in the correlation of anatomical and histological changes with clinically apparent disease (and hence the iconic images of autopsy and microscope), modern pathology studies the causes of disease (etiology) and the expressionevolution of such (pathogenesis) at the. Ron Luff, MD, MPH. Basic Cell Pathology ; Robbins (7th edition), Chapter 1; 2 Cell Injury and Adaptation. Lecture 1- Cell Injury. 4 Inflammation I Compatibility Mode Author rmo5 Created Date 2142011 81918 PM. Definition Cell injury The effect of a variety of stresses due to etiological agents a cell encounters resulting in changes in its internal & external environment. Cellular adaptation o Hyperplasia o Hypertrophy o Atrophy o Metaplasia. Tissue necrosis (from any cause) 5. 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